The Cuban therapeutic vaccine HEBERSaVax against solid tumors is showing positive results in various types of cancer. Including colorectal, hepatocellular carcinoma, ovarian, and renal cancer, in advanced patients. It has potential applications in those with multiple comorbidities, it was announced today.
This active immunotherapy vaccine, developed by the Center for Genetic Engineering and Biotechnology. It is exhibiting few and tolerable adverse effects in Phase II clinical trials.
Moreover these factors allow this candidate to be combined even with conventional therapies without increasing toxicity. Explained Yanelys Morera, the project leader and a full member of the Cuban Academy of Sciences, to the press.
The scientist explained that when a tumor grows, it is an actively growing mass that requires nutrients and oxygen. The vaccine targets the ways in which the tumor obtains nutrients. In addition to triggering cellular responses that halt tumor growth and thus benefit the patient.
We are looking at a candidate with multiple functions. As this product “produces specific antibodies” that cut off blood flow to the tumor. While simultaneously restoring the individual’s ability to attack the cancer with an immune response.
Reporting that the research has gone through several stages, the most recent being the Phase II clinical trials. Also where we have focused on targeting specific locations, she emphasized.
The project leader stressed that this type of therapy is very safe and can even be combined with conventional therapies without increasing toxicity.
Many patients who have received the HEBERSaVax candidate within the framework of the clinical trial have shown significant and positive effects on their quality of life. They have had complete responses, the scientist pointed out.
These results were presented to Cuban President Miguel Díaz-Canel during his regular meeting with experts and scientists on health issues.
With information from Prensa Latina
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